Assessing the Functional Structure of Molecular Transporters by Matthias J.N.Junk PDF

By Matthias J.N.Junk

In his thesis, Matthias Junk takes an cutting edge method of investigate the neighborhood constitution and dynamics of organic and artificial amphiphilic macromolecules able to transporting small molecules. changing the latter with solid radicals, he makes use of state of the art electron paramagnetic resonance (EPR) spectroscopy to explain the hugely appropriate shipping functionality from the perspective of the visitor molecules. Such, he demonstrates that the practical constitution of human serum albumin in answer considerably differs from its crystal constitution – a final result of the protein’s adaptability to host quite a few endogenous compounds and drug molecules. extra, he indicates that the thermal cave in of thermoresponsive hydrogels and dendronized polymers results in static and dynamic heterogeneities at the nanoscale. those heterogeneities undergo effects for the material’s internet hosting houses and permit unexpected advanced catalytic functionalities.

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Assessing the Functional Structure of Molecular Transporters by EPR Spectroscopy (Springer Theses) by Matthias J.N.Junk

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