By Plamen Demirev,Todd R. Sandrin
In the final region century, advances in mass spectrometry (MS) were on the vanguard of efforts to map complicated organic platforms together with the human metabolome, proteome, and microbiome. All of those advancements have allowed MS to develop into a well-established molecular point know-how for microorganism characterization. MS has confirmed its significant virtue as a quick, actual, and reasonably priced technique for microorganism identity, in comparison to traditional phenotypic suggestions. within the final a number of years, purposes of MS for microorganism characterization in study, scientific microbiology, counter-bioterrorism, nutrition defense, and environmental tracking were documented in millions of courses. Regulatory our bodies in Europe, the united states, and in other places have authorized MS-based assays for infectious sickness diagnostics. As of mid-2015, greater than 3300 advertisement MS platforms for microorganism id were deployed world wide in hospitals and scientific labs.
While past paintings has coated broader methods in utilizing MS to signify microorganisms on the species point or above, this ebook makes a speciality of strain-level and subtyping purposes. In twelve person chapters, innovators, leaders and practitioners within the box from worldwide have contributed to a entire review of present and next-generation ways for MS-based microbial characterization on the subspecies and pressure degrees. Chapters contain up to date reference lists in addition to web-links to databases, instructed software program, and different helpful tools.
The emergence of latest, antibiotic-resistant traces of human or animal pathogens is of awesome main issue not just to the clinical and clinical groups, yet to most people in addition. advancements of novel MS-based assays for quick id of lines of antibiotic-resistant microorganisms are reviewed within the e-book in addition. Microbiologists, bioanalytical scientists, infectious sickness experts, medical laboratory and public wellbeing and fitness practitioners in addition to researchers in universities, hospitals, govt labs, and the pharmaceutical and biotechnology industries will locate this e-book to be a well timed and priceless resource.
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Applications of Mass Spectrometry in Microbiology: From Strain Characterization to Rapid Screening for Antibiotic Resistance by Plamen Demirev,Todd R. Sandrin