George M. Rodgers's ADAMTS13: Biology and Disease PDF

By George M. Rodgers

This finished quantity discusses the protease ADAMTS13, summarizing the present prestige of simple and scientific learn. The 9 authoritative chapters commence with a old point of view by means of exploration of the biochemistry and structure-function relationships of ADAMTS13 in addition to its general functionality in hemostasis (cleavage of von Willebrand factor). rising examine topics for ADAMTS13 are coated, together with its strength function in angiogenesis and different elements of mobilephone biology. extra subject matters contain laboratory assays for ADAMTS13, inherited ADAMTS13 deficiency, and bought ADAMTS13 deficiency. A bankruptcy on comparable thrombotic microangiopathic (TMA) issues examines the diversities among TMAs linked to ADAMTS13 deficiency and people no longer linked to ADAMTS13 deficiency. a last bankruptcy studies the initial info on rising points of ADAMTS13, equivalent to the prestige of recombinant ADAMTS13 items and their capability utility.


Comprehensive in its exploration of the ADAMTS13 protease in disease, ADAMTS13: Biology and illness is an important source for scientific hematologists, transfusion medication physicians, and researchers drawn to hemostasis, vascular biology, biochemistry, and metalloproteases.

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ADAMTS13: Biology and Disease by George M. Rodgers

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